首页> 外文期刊>COPD: Journal of Chronic Obstructive Pulmonary Disease >Hospitalization Due to Co-Morbid Conditions is the Main Cost Driver Among Subjects With COPD - A Report From the Population-Based OLIN COPD Study
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Hospitalization Due to Co-Morbid Conditions is the Main Cost Driver Among Subjects With COPD - A Report From the Population-Based OLIN COPD Study

机译:合并疾病导致的住院治疗是COPD患者的主要费用驱动因素-基于人群的OLIN COPD研究报告

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Background: Co-morbidities are common in COPD; however, there is a lack of population-based studies evaluating the health economic impact of co-morbid diseases for subjects with COPD. The main objective of this study was to estimate annual direct health-care costs, divided into costs due to non-respiratory and respiratory conditions, comparing subjects with and without COPD. Methods: Subjects with and without COPD derived from population-based cohorts in northern Sweden have been invited to annual examinations involving spirometry and structured interviews since 2005. This paper is based on data from 1472 subjects examined in 2006. COPD classification was based on spirometry. Results: Mean annual costs for both respiratory and non-respiratory conditions were significantly higher for subjects with COPD than non-COPD subjects, in total USD 2139 vs. USD 1276 (p = 0.026), and COPD remained significantly associated with higher costs also after adjustment for common confounders as age, smoking habits, BMI and sex. The mean total cost increased with COPD disease severity and was higher for all severity stages (GOLD) than for non-COPD subjects. Hospitalization due to non-respiratory diseases was the main cost driver in COPD, after adjustment for common confounders amounting to about 46% (unadjusted 62%) of the total COPD-costs. Conclusions: Costs were higher for COPD than non-COPD. In COPD, costs for co-morbid conditions were higher than those for respiratory conditions, and hospitalization due to co-morbid conditions was the main cost driver also when adjusted for common confounders.
机译:背景:合并症在COPD中很常见。但是,缺乏基于人群的研究来评估合并症对COPD患者的健康经济影响。这项研究的主要目的是估计年度直接医疗保健费用,将其分为因非呼吸和呼吸状况引起的费用,比较有无COPD的受试者。方法:自2005年以来,瑞典北部以人口为基础的队列中有无COPD的受试者已被邀请参加涉及肺活量测定和结构化访谈的年度检查。本文基于2006年检查的1472名受试者的数据。COPD分类基于肺活量测定。结果:患有COPD的受试者在呼吸和非呼吸疾病方面的平均年度费用均显着高于非COPD受试者,总计2139美元与1276美元(p = 0.026),并且COPD仍与费用增加显着相关调整常见混杂因素,例如年龄,吸烟习惯,BMI和性别。平均总费用随COPD疾病严重程度而增加,并且在所有严重程度阶段(GOLD)均高于非COPD受试者。非呼吸系统疾病导致的住院治疗是COPD的主要成本驱动因素,对常见混杂因素进行调整后,占COPD总费用的46%(未经调整的为62%)。结论:COPD的成本高于非COPD。在COPD中,合并症的费用高于呼吸道疾病的费用,而合并症导致的住院费用也是调整普通混杂因素的主要成本驱动因素。

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