Turn Conformation of beta-Amino Acid-Based Short Peptides Promoted by an Amidothiourea Moiety at C-Terminus

摘要

A C-terminal amidothiourea motif is shown to promote a beta-turn-like folded conformation in a series of beta-amino acid-based short peptides in both the solid state and solution phase by an intramolecular 11-membered ring hydrogen bond.