Stigma associated with radiation induced bowel injury (RBI) has restricted interest in its pathogenesis and the pathophysiological processes that occur as a consequence. This neglect has in turn hampered clinical management and led to the widely held belief that RBIs are not amenable to treatment. RBI is more common than Crohn's disease, yet attracts a fraction of the research funding. Furthermore, only a fifth of atients with RBI in the UK see a gastroenterologist, and most who do so are managed ineffectively.
展开▼