Re: Prostate-Specific Antigen (PSA) concentrations in hypogonadal men during 6 years of transdermal testosterone treatment: Editorial comment

摘要

Editorial Comment: A follicle-stimulating hormone assay and the measurement of testis longitudinal axis can reliably predict whether azoospermia is due to obstruction or spermatogenic dysfunction, obviating the need for diagnostic testis biospy. Additionally no number of prior negative biopsies excludes success with microsurgical testis sperm extraction, rendering diagnostic biopsy useless at best. This investigator provides evidence that a diagnostic biopsy may even be harmful by decreasing the likelihood of surgical sperm retrieval afterward. It is time to eliminate the practice of performing a testis biopsy purely for histological diagnosis.