首页> 外文期刊>International Journal of Pharmaceutics >Effect of the product type, of the amount of applied sunscreen product and the level of protection in the UVB range on the level of protection achieved in the UVA range
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Effect of the product type, of the amount of applied sunscreen product and the level of protection in the UVB range on the level of protection achieved in the UVA range

机译:产品类型,防晒产品的用量和UVB范围内的防护等级对UVA范围内达到的防护等级的影响

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摘要

Using a topical product is part of the overall strategy for skin cancer prevention. The level of protection attainable when using commercial products is indicated by the Sun Protection Factor (SPF) value, in use everywhere. This value reflects the level of protection primarily in the UVB range. However, UVA radiation also has deleterious effects on the skin, and it is essential to prevent it, which is why products must offer a wide spectrum of protection. Tests conducted in vivo, before any marketing, are done by applying the studied product at a rate of 2.0 mg cm(-2), while users, in practice, only use 1.0-1.5 mg cm(-2). We now know that this reduction in the amount of applied product greatly affects the SPF. To complete the state of knowledge in this area, we sought to evaluate the effect of a decrease in the amount of applied sunscreen product by studying sunscreen creams and oils on the level of protection attainable in the UVA range. We have shown that the PF-UVA is divided by a factor of 2.2, on average, when the amount of applied product is reduced by half, with differences depending on the product type under consideration (cream or oil) and depending on the SPF of the preparation. (C) 2016 Elsevier B.V. All rights reserved.
机译:使用外用产品是预防皮肤癌总体策略的一部分。使用商业产品时可获得的保护级别由普遍使用的防晒系数(SPF)值指示。该值主要反映在UVB范围内的防护等级。但是,UVA辐射也会对皮肤产生有害影响,因此必须加以预防,这就是为什么产品必须提供广泛保护的原因。在进行任何市场营销之前,都应通过以2.0 mg cm(-2)的比例施用被研究产品来进行体内测试,而用户实际上只使用1.0-1.5 mg cm(-2)。现在我们知道,减少产品用量会极大地影响SPF。为了完善该领域的知识水平,我们试图通过研究防晒霜和油类对UVA范围内可达到的防护水平来评估减少防晒产品用量的影响。我们已经证明,当所用产品的量减少一半时,PF-UVA平均除以2.2的系数,其差异取决于所考虑的产品类型(奶油或油脂)以及SPF的SPF。准备。 (C)2016 Elsevier B.V.保留所有权利。

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