Green and Effective One-Pot Synthesis of 5-Oxo-pyrazoIidine and 5-Amino-2,3-dihydro-1H-Pyrazole Derivatives through Ball Milling Under Catalyst-Free and Solvent-Free Conditions

摘要

A high-yield synthesis memod for the one-pot synthesis of new 5-oxo-pyrazolidine and 5-amino-2,3-dihydro-1H-pyrazole derivatives was developed using ball milling under solvent-free and catalyst-free conditions. The proposed method is simple, economical and eco-friendly.