ANTIBACTERIAL ACTIVITY AND ANTIFUNGAL ANDANTI-MYCOTOXIGENIC ACTIVITIES AGAINST ASPERGILLUSFLAVUS AND A. OCHRACEUS OF GREEN COFFEECHLOROGENIC ACIDS AND DODECYL CHLOROGENATESMIRNA

摘要

Green coffee chlorogenic acids (CGA) and dodecyl chlorogenates (DCGA) werescreened for their in vitro antimicrobial activity on different bacterial strains(Bacillus cereus, Clostridium sporogenes, Listeria innocua, Micrococcus luteus, Staphylococcus aureus, Escherichia coli, Pseudomonas fluorescens, Salmonella enterica),and for their antifungal and anti-mycotoxigenic activities against Aspergillus flavusand A. ochraceus. Sa. enterica was resistant to both CGA and DCGA. CGA had anantimicrobial effecton gram-positive and gram-negative bacteria; it exhibitedbactericidal activity against P. fluorescens and S. aureus, and had no sporicidalactivity against B. cereus and C. sporogenes. DCGA was active on three grampositive bacteria and inactive on the gram-negative ones. Both, CGA and DCGApresented anti-Aspergillus activities and were better anti-mycotoxigenic agentsfor ochratoxin A than for aflatoxin B1. This work reports for the first time bothCGA and DCGA as antibacterial, antifungal and anti-mycotoxigenic agents, whichcould be promising preservatives in food or nonfood products.