Rapid advances in genomics and related technologies are promising a new era of personalized healthcare and disease prevention, not limited to new drugs, but also involving diagnostic and screening biomarkers. Although scientists have put forward the hypothesis that the time of personalized medicine has come (or will soon arrive), the chasm between new discoveries and the clinical use of new insights is wide. The gap between discovery and clinical implementation of diagnostic testing has made it necessary close cooperation between different stakeholders to accelerate and streamline the effective translation of validated knowledge into daily medical practice [1, 2]. Several lines of evidence suggest, however, that translation of new insights gathered from basic research studies as well as from clinical research per se is substantially biased.
展开▼
