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Isolating active ingredients in a parent-mediated social communication intervention for toddlers with autism spectrum disorder

机译:在自闭症谱系障碍患儿父母介导的社交交流干预中分离有效成分

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Background: Behavioral interventions are commonplace in the treatment of autism spectrum disorders, yet relatively little is known about how and why these interventions work. This study tests the relationship between isolated core components of a packaged social communication intervention and the primary outcome, joint engagement, to better understand how the intervention is affecting change in individuals. Methods: A total of 86 toddlers and their parents were enrolled in the study and randomized to one of two treatments, the joint attention, symbolic play, engagement, and regulation (JASPER) parent-mediated intervention or a psychoeducational intervention. Measures regarding the parent's use of intervention strategies were collected before and after the 10-week intervention. Additional measures of child and parent joint engagement were also collected. Results: A significant effect of treatment was found for all four of the core strategies of the intervention, favoring a larger increase in the JASPER condition. A hierarchical linear regression revealed several individual predictors of joint engagement, including parent-rated buy-in, interventionist-rated parent involvement, and parental use of strategies. To complement the hierarchical analysis, we also tested the potential mediating effect the strategies may have on the relationship between treatment and joint engagement. Results showed that the strategy of mirrored pacing mediated the relationship between treatment and joint engagement in the positive direction. Conclusions: These results strongly suggest that the mirrored pacing strategy is an active ingredient of the JASPER treatment.
机译:背景:行为干预在自闭症谱系障碍的治疗中很普遍,但是对于这些干预的作用方式和作用却知之甚少。这项研究测试了一揽子社会沟通干预措施的孤立核心组成部分与主要结果(联合参与)之间的关系,以更好地了解干预措施如何影响个人的变化。方法:共有86名幼儿及其父母参加了这项研究,并随机接受了两种治疗方法之一,即联合注意,象征性游戏,参与和调节(JASPER)父母介导的干预或心理教育干预。在10周干预之前和之后,收集有关父母使用干预策略的措施。还收集了儿童和父母共同参与的其他措施。结果:在干预的所有四个核心策略中均发现了显着的治疗效果,有利于JASPER病情的更大增加。分层线性回归揭示了联合参与的几个单独的预测因素,包括父母评估的买入,干预主义者评估的父母参与以及父母对策略的使用。为了补充层次分析,我们还测试了该策略可能对治疗和关节活动之间的关系产生潜在的中介作用。结果表明,镜像起搏策略在积极方向上介导了治疗与关节活动之间的关系。结论:这些结果强烈表明,镜射起搏策略是JASPER治疗的有效成分。

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