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Prognosis of patients with COPD admitted to the ICU.

机译:入ICU的COPD患者的预后。

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We read with interest the article by Wildman a al} They have carried out an interesting study on patients with chronic obstructive pulmonary disease (COPD) or asthma admitted to the Intensive Care Unit (ICU). The authors in their discussion state that their overall results may be least applicable to patients on long-term oxygen (LTO) and/or with low functional scores. Intubated patients with COPD on LTO constitute 10.4% of 394 intubated patients in this study. Only mortality results relating to this population are shown in this article. It would have been interesting to show results such as quality of life at 180 days. If deciding to intubate is difficult in patients with exacerbated COPD, it is more difficult in those patients on LTO. Clinicians tend to be pessimistic about survival and quality of life and they are very selective when admitting these patients. In 1999 we reported on a study2 which focused on patients with exacerbated COPD on LTO who were mechanically ventilated. Mortality was higher than that reported by Wildman a al in this subgroup of patients: 35% (in ICU), 50% (in hospital), 75% (at 1 year) and 85% (at 5 years). Patients who died in hospital and in the first year after discharge had a lower forced expiratory volume in 1 s (FEVj) than survivors. Although the study was carried out in a University tertiary hospital, the sample size was small (20 patients recruited in 2 years).
机译:我们感兴趣地阅读了Wildman等人的文章。他们对重症监护病房(ICU)患有慢性阻塞性肺疾病(COPD)或哮喘的患者进行了有趣的研究。作者在讨论中指出,他们的总体结果可能最不适合长期使用氧气(LTO)和/或功能评分低的患者。在这项研究中,LTO的COPD插管患者占394例插管患者的10.4%。本文仅显示与该人群有关的死亡率结果。显示诸如180天生活质量之类的结果会很有趣。如果COPD恶化的患者难以插管,则接受LTO的患者难度更大。临床医生往往对生存和生活质量感到悲观,并且在接纳这些患者时非常有选择性。在1999年,我们报道了一项研究2,研究对象为机械通气的LTO加重COPD的患者。在该亚组患者中,死亡率高于Wildman等报告的死亡率:35%(在ICU中),50%(在医院中),75%(在1岁时)和85%(在5岁时)。在医院死亡和出院后第一年死亡的患者在1 s(FEVj)内的呼气量低于幸存者。尽管该研究是在大学三级医院进行的,但样本量很小(两年内招募了20名患者)。

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