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Intracranial pressure monitoring in brain-injured patients is associated with worsening of survival.

机译:脑损伤患者的颅内压监测与生存恶化有关。

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I am writing to comment on the article "Intracranial Pressure Monitoring in Brain-Injured Patients is Associated With Worsening of Survival" by Shafi et al., published in the February issue the Journal of Trauma. This study shows that if you stratify patients using sufficiently insensitive data, you can come up with interesting and very questionable results. The National Trauma Data Bank (NTDB) is not a brain injury database and, therefore, does not index those variables (outside of GCS and age) that have been repeatedly suggested as predictive of outcome and are routinely required to be independently controlled as confounding variables in traumatic brain injury (TBI) outcome studies (i.e., early hypotension, pupillary response, and CT diagnosis).2 The absence of these specific data makes the NTDB a particularly poor platform for TBI studies.
机译:我写这篇文章的评论是Shafi等人的文章“脑损伤患者的颅内压监测与生存恶化有关”,该文章发表在2月刊《创伤杂志》上。这项研究表明,如果您使用足够不敏感的数据对患者进行分层,则会得出有趣且非常可疑的结果。国家创伤数据库(NTDB)不是脑损伤数据库,因此,不会索引那些反复被认为可预测结果且通常需要作为混杂变量进行独立控制的变量(GCS和年龄除外)在创伤性脑损伤(TBI)结果研究(即早期低血压,瞳孔反应和CT诊断)中进行了研究。2由于缺少这些具体数据,NTDB成为TBI研究的特别差的平台。

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