Aerobic exercise and not a diet supplemented with jussara acai (Euterpe

摘要

The pulp of jussara acai (Euterpe edulis Martius) fruit is rich in anthocyanins that exert antioxidant and anti-inflammatory effects similar to those exerted by aerobic exercise. In the present study, we investigated the effects of jussara acai fruit pulp consumption, either alone or in combination with aerobic exercise, on the hepatic oxidative and inflammatory status of ApoE-deficient (ApoE(-/-)) mice. Male mice were divided into four groups (control (C), control plus acai, exercise plus acai (EXA) and exercise (EX)) and fed the AIN-93M diet or the AIN-93M diet formulated to contain 2% freeze-dried acai pulp. Mice in the EX and EXA groups were subjected to a progressive running programme (5 d/week, 60 min/d, 16 m/min) for 12 weeks. Mice that were made to exercise exhibited reduced (40.85 %; P<0.05) hepatic superoxide dismutase activity when compared with the C mice, independent of the acai diet. Mice in the EX group exhibited a lower (42 %; P<0.05) mRNA expression of monocyte chemotactic protein-1 in the liver compared with the C mice. Mice in the EXA and EX groups had lower percentages of hepatic lipid droplets (70% and 56 %, respectively; P<0.05) when compared with the C mice. Mice in the EX group had smaller (58 %; P<0.05) area of lesions in the aorta when compared with the C mice. Serum lipid profile was not affected (P>0.05). In conclusion, aerobic exercise training rather than acai fruit pulp consumption or a combination of both enhances the hepatic oxidative and inflammatory status of ApoE(-/-) mice