A measurement method for determining the correlation between the amount of haemolysis and the electric current in low-temperature plasma treatment

摘要

We have developed a low-temperature plasma apparatus as a surgical device for haemostasis. A quantitative measurement method and system that analyses the relationship between the properties of low-temperature plasma and blood components are necessary to evaluate the performance and safety of plasma apparatuses. In a previous study, we revealed that low-temperature plasma haemolyses erythrocytes, and the released haemoglobin contribute to clot formation; haemolysis by low-temperature plasma occurs when the value of the current originating from low-temperature plasma exceeds a certain threshold. In the current study, we examined the correlation between the haemoglobin concentration and the electric current value through experiments using our improved measurement system. We propose a method to control the haemolysis effect by adjusting the plasma current value.