Brain structural damage in spinocerebellar ataxia type 1

A. Ginestroni; R. Della Nave; C. Tessa; M. Giannelli; D. De Grandis; R. Plasmati; F. Salvi; S. Piacentini; Prof. M. Mascalchi

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Brain structural damage in spinocerebellar ataxia type 1

机译：脊髓小脑共济失调1型的脑结构损伤

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摘要

Neuropathological description of the brain in spinocerebellar ataxia type 1(SCA1) is limited to a few cases. Voxel-based morphometry (VBM) enables an unbiased in vivo whole-brain quantitative analysis of regional differences in gray matter (GM) and white matter (WM) volume. We assessed with VBM the structural damage in patients with genetically confirmed SCA1.

机译：脊髓小脑性共济失调1型（SCA1）的大脑的神经病理学描述仅限于少数情况。基于体素的形态计量学（VBM）可以对灰质（GM）和白质（WM）体积的区域差异进行无偏差的体内全脑定量分析。我们用VBM评估了遗传学确诊的SCA1患者的结构损伤。

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来源
《Journal of Neurology》 |2008年第8期|1153-1158|共6页
作者
A. Ginestroni; R. Della Nave; C. Tessa; M. Giannelli; D. De Grandis; R. Plasmati; F. Salvi; S. Piacentini; Prof. M. Mascalchi;
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作者单位

Radiodiagnostic Section Dept. of Clinical Physiopathology University of Florence Viale Morgagni 85 50134 Florence Italy;

Radiodiagnostic Section Dept. of Clinical Physiopathology University of Florence Viale Morgagni 85 50134 Florence Italy;

Radiology Unit Versilia Hospital Camaiore (Lucca) Italy;

Medical Physics University of Pisa Pisa Italy;

Dept. of Neurology Rovigo Hospital Rovigo Italy;

Division of Neurology Bellaria Hospital Bologna Italy;

Division of Neurology Bellaria Hospital Bologna Italy;

Dept. of Neurological and Psychiatric Sciences University of Florence Florence Italy;

Radiodiagnostic Section Dept. of Clinical Physiopathology University of Florence Viale Morgagni 85 50134 Florence Italy;

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正文语种 eng
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关键词
voxel-based morphometry; MR imaging; ataxia; spinocerebellar ataxia type 1;

机译：基于体素的形态计量学;MR成像;共济失调;脊髓小脑共济失调1型;

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专利

1. Brain structural damage in spinocerebellar ataxia type 1 : a VBM study. [J] . Ginestroni A, Della-Nave R, Tessa C, Journal of neurology . 2008,第8期

机译：脊髓小脑性共济失调1型的脑结构损害：一项VBM研究。
2. Brain Structural Damage in Spinocerebellar Ataxia Type 2. A Voxel-Based Morphometry Study [J] . Riccardo Delia Nave, Andrea Ginestroni, Carlo Tessa Movement disorders . 2008,第6期

机译：2型脊髓小脑共济失调的大脑结构损伤。基于体素的形态计量学研究
3. Brain structural damage in spinocerebellar ataxia type 2. A voxel-based morphometry study. [J] . Della-Nave R, Ginestroni A, Tessa C, Movement disorders . 2008,第6期

机译：2型脊髓小脑共济失调的大脑结构损伤。基于体素的形态学研究。
4. Role of EMG Rectification for Corticomuscular and Intermuscular Coherence Estimation of Spinocerebellar Ataxia Type 2 (SCA2) [C] . Y. Ruiz-Gonzalez, L. Velazquez-Perez, R. Rodriguez-Labrada, Iberoamerican congress on pattern recognition . 2019

机译：EMG矫正对2型脊髓小脑共济失调（SCA2）的皮质肌和肌间相干估计的作用。
5. Infant Onset Spinocerebellar Ataxia Type 13 Mutation Leads to Developmental and Rapid Degenerative Phenotypes Related to Hyperexcitability in Purkinje Cells [D] . Ulrich, Brittany Nicole. 2017

机译：婴儿起病的脊髓小脑共济失调13型突变导致发展和快速退化的表型与浦肯野细胞过度兴奋有关。
6. Intra- and Inter-Modular Connectivity Alterations in the Brain Structural Network of Spinocerebellar Ataxia Type 3 [O] . Chi-Wen Jao, Bing-Wen Soong, Tzu-Yun Wang, 2019

机译：纺丝大脑结构网络脑结构网络中的和模块间连通性改变3型3
7. Progression of microstructural damage in spinocerebellar Ataxia Type 2: A longitudinal DTI study [O] . Mascalchi, M, Toschi, N, Giannelli, M, 2015

机译：2型脊髓小脑共济失调的微结构损伤进展：纵向DTI研究

Brain structural damage in spinocerebellar ataxia type 1

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