Implication of the bioelectronic principle in cancer therapy: treatment of cancer patients by methylglyoxal-based formulation

摘要

Based on our previous in vitro studies with human cells and in vivo studies with animals we had developed an anticancer formulation with methylglyoxal as the lead ingredient. This formulation has a tumoricidal effect by inhibiting specifically in cancerous cells, the electron flow and the transfer of redicing equivalent necessary for the production of adenosine-5'-triphosphate (ATP), the cellular energy currency. By keeping this remarkable property in mind, we had treated 24 patients suffering from different types of malignancy (mostly in very advanced Stage of the disease) with this methylglyoxal-based formulation.