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Dataset of allele, genotype and haplotype frequencies of four polymorphisms filaggrin gene in Russian patients with atopic dermatitis

机译:俄罗斯特应性皮炎患者四种多态性Filaggrin基因的等位基因,基因型和单倍型频率的数据集

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摘要

Data on the allele, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) (rs3126085, rs12144049, rs471144 and rs4363385)filaggrin(FLG) gene in Russian patients with atopic dermatitis are presented. Genome-wide association studies identified these SNPs could be significant genetic markers associated with atopic dermatitis. The frequencies of alleles, genotypes and haplotypes of four SNPs were calculated in 3 groups: entire sample, females and males. No significant differences in the allele, genotype and haplotype frequencies between males and females with AD patients were observed.
机译:提出了关于四种单核苷酸多态性(SNP)(SNP)(RS3126085,RS12144049,RS47114449,RS471144和RS4363385)的基因型,基因型和单倍型频率,俄罗斯特应性皮炎的俄罗斯特应性皮炎患者的Filaggrin(FLG)基因。基因组 - 范围协会研究发现这些SNP可能是与特应性皮炎相关的重要遗传标记。在3组中计算等位基因,基因型和单倍型的频率:整个样品,女性和雄性。观察到雄性和女性之间的等位基因,基因型和单倍型频率无显着差异。

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