SAT-436 CLINICAL AND GENETIC CHARACTERISTICS OF?AUTOSOMAL RECESSIVE POLYCYSTIC KIDNEY DISEASE (ARPKD) PATIENTS FROM OMAN AND PKHD1 FOUNDER MUTATIONS

摘要

Introduction: The Omani population has a high prevalence of rare ge-netic disorders, and their study provides unique clinical and geneticinsights. Autosomal recessive polycystic kidney disease (ARPKD) is oneof the leading causes of kidney and liver-associated morbidity andmortality in the country. We aimed to describe the clinical and geneticprofile of ARPKD patients from Oman.