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The Additive Interaction between Body Mass Index and Hypertension Family History in Han and Yugur: The China National Health Survey (CNHS)

机译:汉族和玉石体重指数与高血压家族史之间的添加剂相互作用:中国国家卫生调查(CNHS)

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Objective. To estimate the additive interaction of body mass index (BMI) and family history of hypertension (FHH) on hypertension and explore whether the interaction could be influenced by behavioural risk factors. Methods. The cross-sectional data on 5791 participants were from the China National Health Survey in Gansu province in 2016. We assessed the additive interaction by calculating the relative excess risk due to interaction (RERI), the attributable proportion due to interaction (AP), and the synergy index (SI). Results. ORs for hypertension were highest in Han (13.52, 95% CI: 9.45 to 19.34) and Yugur (13.85, 95% CI: 8.48 to 22.63) with the combination of obesity and FHH. The interaction of BMI and FHH was significant in Han people, with the RERI, AP, and SI and their 95% CIs being 2.48 (1.13 to 3.82), 0.33 (0.19 to 0.47), and 1.61 (1.26 to 2.07) for overweight and FHH and 6.32 (1.91 to 10.73), 0.47 (0.27 to 0.67), and 2.02 (1.33 to 3.07) for obesity and FHH, respectively. The interaction of BMI and FHH was not significant in Yugur people. Adjustment for behavioural risk factors had little influence on the interactions, and risks of hypertension remained increased. Conclusions. BMI and FHH were associated with hypertension, and the interaction of BMI and FHH on hypertension was significant in Han but not in Yugur people. Behavioural risk factors had little influence on the associations and interactions. The exacerbation of hypertension risks by overweight or obesity in hypertension families deserves attention in weight control and community care.
机译:客观的。估计体重指数(BMI)的添加剂相互作用和高血压(FHH)的家族史(FHH)对高血压的影响,并探讨相互作用是否受到行为风险因素的影响。方法。 2016年,5791名参与者的横断面数据来自中国国家卫生调查2016年。我们通过计算互动(RERI),互动(AP)引起的可归因比例来评估添加剂相互作用。协同指数(SI)。结果。汉族高血压(13.52,95%:9.45至19.34)和yugur(13.85,95%CI:8.48至22.63),具有肥胖症和FHH的组合。 BMI和FHH的相互作用在汉族人中显着,RERI,AP和SI,其95%CIS为2.48(1.13至3.82),0.33(0.19至0.47),和1.61(1.26至2.07)的超重和FHH和6.32(1.91至10.73),0.47(0.27至0.67),肥胖和FHH分别为2.02(1.33至3.07)。 BMI和FHH的相互作用在yugur人中并不重要。行为风险因素的调整对相互作用影响不大,高血压风险仍然增加。结论。 BMI和FHH与高血压有关,BMI和FHH对高血压的相互作用在汉语中显着,但不在yugur人。行为风险因素对协会和互动影响很小。高速或高血压家庭的超重或肥胖的加剧的高血压风险值得关注体重控制和社区护理。

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