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UV-Visible Spectrophotometric Method Development and Validation of Assay of Paracetamol Tablet Formulation

机译:紫外可见分光光度法的开发和对乙酰氨基酚片剂配方测定的验证

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摘要

A novel,safe and sensitive method of spectrophotometric estimation in UV-region has been developed for the assay of Paracetamol in its tablet formulation. The method have been developed and validated for the assay of Paracetamol using Methanol and water as diluents. Which does not shows any interference in spectrophotometric estimations. All the parameters of the analysis were chosen according to ICH [Q2(R1)] guideline and validated statistically using RSD and %RSD along with neat chromate grams.
机译:已经开发了一种新颖,安全,灵敏的紫外区分光光度法估算片剂中扑热息痛的含量。该方法已开发并验证了使用甲醇和水作为稀释剂的扑热息痛的测定方法。在分光光度估计中没有显示任何干扰。分析的所有参数均根据ICH [Q2(R1)]指南进行选择,并使用RSD和%RSD以及纯铬酸盐进行统计验证。

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