The Selective Phosphodiesterase-5 Inhibitor Tadalafil Induces Microvascular and Metabolic Effects in Type 2 Diabetic Postmenopausal Females

Giuseppe Murdolo; Mikaela Sj?strand; Lena Strindberg; Peter L?nnroth; Per-Anders Jansson

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The Selective Phosphodiesterase-5 Inhibitor Tadalafil Induces Microvascular and Metabolic Effects in Type 2 Diabetic Postmenopausal Females

机译：选择性磷酸二酯酶5抑制剂他达拉非诱导2型糖尿病绝经后女性的微血管和代谢作用。

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Objective:The objective of the study was to explore the acute in vivo effects of the selective phosphodiesterase-5 inhibitor tadalafil on local microcirculation and regional metabolism in skeletal muscle and adipose tissue (AT).

机译：目的：本研究的目的是探讨选择性磷酸二酯酶5抑制剂他达拉非对骨骼肌和脂肪组织（AT）局部微循环和局部代谢的急性作用。

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《The journal of clinical endocrinology and metabolism》 |2013年第1期|共10页
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Giuseppe Murdolo; Mikaela Sj?strand; Lena Strindberg; Peter L?nnroth; Per-Anders Jansson;
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中图分类代谢病;
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1. Phosphodiesterase-5 inhibitor tadalafil attenuates oxidative stress and protects against myocardial ischemia/reperfusion injury in type 2 diabetic mice [J] . Saisudha Koka, Anindita Das, Fadi N. Salloum, Free Radical Biology and Medicine: The Official Journal of the Oxygen Society . 2013,第Jula期

机译：磷酸二酯酶5抑制剂他达拉非可减轻2型糖尿病小鼠的氧化应激并防止心肌缺血/再灌注损伤
2. Chronic treatment with long acting phosphodiesterase-5 inhibitor tadalafil alters proteomic changes associated with cytoskeletal rearrangement and redox regulation in Type 2 diabetic hearts [J] . Basic Research in Cardiology: Official Journal of the German Association of Cardiovascular Research . 2012,第2期

机译：长效磷酸二酯酶-5抑制剂他达拉非的慢性治疗改变了2型糖尿病心脏中与细胞骨架重排和氧化还原调节相关的蛋白质组学变化
3. Chronic treatment with long acting phosphodiesterase-5 inhibitor tadalafil alters proteomic changes associated with cytoskeletal rearrangement and redox regulation in Type 2 diabetic hearts [J] . Saisudha Koka, Lei Xi, Rakesh C. Kukreja Basic Research in Cardiology . 2012,第2期

机译：长效磷酸二酯酶-5抑制剂他达拉非的慢性治疗改变了2型糖尿病心脏中与细胞骨架重排和氧化还原调节相关的蛋白质组学变化
4. The Effects of an Exercise Intervention on Cardiovascular Risk Factors in Postmenopausal Type 2 Diabetics [C] . J.C. Orri, C.J. Thompson, D.E. Sellmeyer International Congress on Coronary Artery Disease . 2007

机译：运动干预对绝经后2型糖尿病患者心血管危险因素的影响
5. Enhancement of antitumor effects of doxorubicin with phosphodiesterase-5 inhibitors. [D] . Qureshi, Ian Z. 2008

机译：磷酸二酯酶5抑制剂增强阿霉素的抗肿瘤作用。
6. Long-acting phosphodiesterase-5 inhibitor tadalafil induces sustained cardioprotection against lethal ischemic injury [O] . Nauman Ahmad, Yigang Wang, Ailia K. Ali, -1

机译：长效磷酸二酯酶5抑制剂他达拉非（tadalafil）诱导持续的心脏保护作用抵抗致命性缺血性损伤
7. The Selective Phosphodiesterase-5 Inhibitor Tadalafil Induces Microvascular and Metabolic Effects in Type 2 Diabetic Postmenopausal Females [O] . Giuseppe Murdolo, Mikaela Sjöstrand, Lena Strindberg, 2013

机译：选择性磷酸二酯酶-5抑制剂Tadalafil在2型糖尿病绝经后女性中诱导微血管和代谢效应

The Selective Phosphodiesterase-5 Inhibitor Tadalafil Induces Microvascular and Metabolic Effects in Type 2 Diabetic Postmenopausal Females

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