Association analysis of polymorphism in KIAA1717, HUMMLC2B, DECR1 and FTO genes with meat quality traits of the Berkshire breed

摘要

Single nucleotide polymorphisms (SNPs) in?KIAA1717, HUMMLC2B, DECR1, andFTO?genes have been found to be associated with some pork meat quality traits. In this study, we discovered that, in addition to meat quality traits reported previously, SNPs in these genes also are significantly associated with other meat quality traits in the?Berkshire?breed. A total of 323?Berkshire?pigs bred under the same conditions were used for meat quality evaluation and polymerase chain reaction-amplified genes with restriction endonucleases (PCR-RFLP) genotyping analyses. The association analysis of RFLP genotyping with meat quality traits revealed that the SNPs in these 4 genes have novel associations with multiple meat quality traits (p < 0.01 or p < 0.05); a SNP in?KIAA1717?was associated with meat color (CIE L), backfat thickness, drip loss, water-holding capacity, and pH24hr; a SNP in?HUMMLC2B?was associated with chemical composition (collagen), drip loss, shear force, and pH24hr; a SNP in?DECR1?was associated with meat color (CIE?a and b) and backfat thickness; and a SNP in?FTO?was associated with meat color (CIE L, a and b), protein content, drip loss, and water-holding capacity. Taken collectively, our results suggest that these 4 SNPs may be used for marker-assisted selection as a genetic marker for meat quality traits in?Berkshire?pigs.