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Toxicity of Chiral Pesticide Rac- Metalaxyl and R- Metalaxyl to Daphnia magna

机译:手性农药Rac-甲霜灵和R-甲霜灵对水蚤的毒性

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摘要

Chirality in pesticides has become a challenge because of enantiomers’ different toxicities to non-target organisms. Acute and chronic toxicities of Rac-metalaxyl and R-metalaxyl to Daphnia magna were determined and compared. The 48-h LC50 for Rac- and R-metalaxyl to Daphnia magna were 51.5 and 41.9 mg/L. In a 14-day chronic test, the lowest-observed-effective concentration (LOEC) and no-observed-effective concentration (NOEC) of Rac-metalaxyl were 2 and 1 mg/L, respectively, whereas those of R-metalaxyl were 1 and 0.1 mg/L. Body length, days-to-first-brood and number of broods per female were significantly (p 1.0 mg/L, but affected by Rac-metalaxyl at ≥2.0 mg/L.
机译:由于对映异构体对非目标生物的毒性不同,因此农药中的手性已经成为一个挑战。测定并比较了Rac-甲霜灵和R-甲霜灵对大型蚤的急性和慢性毒性。 Rac-和R-甲霜灵至大型蚤的48小时LC50为51.5和41.9 mg / L。在14天的长期测试中,Rac-甲霜灵的最低观测有效浓度(LOEC)和无观测有效浓度(NOEC)分别为1 mg / L,而R-甲霜灵的最低有效浓度为1 mg / L和0.1 mg / L。体长,初次产卵天数和每位女性的产卵数均显着(p 1.0 mg / L,但≥2.0mg / L受Rac-甲霜灵影响。

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