FIELD: toxicology, in particular determination of water flea sensibility to toxic effect of water-soluble chemicals.;SUBSTANCE: claimed method includes detection of water flea death time (min) caused by water-soluble chemicals, wherein concentration (C, mol/l) of chemical under consideration fluctuates according to logarithmic scale with interval of 0.1. Plot of Y versus X is made, wherein Y-axis represents average death time with scale of 1 point = 1 min; X-axis represents reverse concentration (1/C) of chemical under consideration; and scale is proportional to log increasing by 0.1. Water flea sensibility to toxic effect (tg) is calculated according to equation: tg = TL(min):1/KL = TL(min)xKl (I), wherein is inclination of straight line to X-axis; TL(min) is death time (min) being determined according to point of hypothetical crosspoint of straight line with Y-axis; KL is lethality constant (mol/l) defined as chemical concentration wherein water flea death time is equal to 2TL(min).;EFFECT: Method allowing evaluation of toxic effect evolution dynamics and comparison of toxic effect of water-soluble chemicals in equal concentration ranges.;2 tbl, 1 ex, 1 dwg
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机译：领域：毒理学，特别是测定水蚤对水溶性化学物质毒性作用的敏感性。;要求保护的方法包括检测由水溶性化学物质引起的水蚤死亡时间（min），其中浓度（C，mol / l所考虑化学药品的）根据对数刻度以0.1为间隔波动。绘制了Y与X的关系图，其中Y轴表示平均死亡时间，比例为1分= 1分钟; X轴表示所考虑化学物质的反向浓度（1 / C）;比例与对数成正比，增加0.1。根据以下公式计算水蚤对毒性作用的敏感性（tg）：tg = T L（min）：1 / K L = T L（min） xK l （I），其中，直线相对于X轴的倾斜度; T L（min）是根据与Y轴的直线的假想交叉点确定的死亡时间（min）; K L 是致死常数（mol / l），定义为化学浓度，其中水蚤死亡时间等于2T L（min）。浓度范围内水溶性化学品的化学作用演化动力学和毒性比较[2] tbl，1 ex，1 dwg
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