Hypolipidaemic effect of maize starch with different amylose content in ovariectomized rats depends on intake amount of resistant starch

摘要

The effect of amylose content on digestibility of starch in the small intestine and on the concentration of plasma lipid were studied in ileorec-ntostomized rats and in ovariectomized rats, respectively. Seven kinds of starch with different amylose content (0, 27, 54, 62, 76, 79, 86%) werenused as test starch, which contained 0·4, 5·6, 37·1, 40·2, 45·6, 36·9 and 36·1% resistant starch (RS), respectively. Rats were fed one of test dietsncontaining 30% test starch with different amylose content for 14 d in ileorectostomized and for 21 d in ovariectomized rats. Food intake was notnsignificantly different among the groups. In ileorectostomized rats, the small intestinal starch digestibility decreased with increasing intakes ofnamylose and RS. In ovariectomized rats, body weight gain was lower on the higher amylose maize starch diets. The concentrations of plasmanTAG and cholesterol decreased with increasing intake of RS. The concentrations of liver total lipids and TAG decreased with increasingnintake of RS, but that of liver cholesterol did not. There was significant positive correlation between the level of sterol regulatory element-bindingnprotein-1c mRNA and concentration of liver TAG. Total SCFA amount in the caecum increased logarithmically with increasing dry weight ofncaecal contents. The amount of bile acids in the small intestinal content and the excretions of bile acids and neutral steroids in faeces increasednwith increasing RS intake. These results show that starch rich in RS is more effective in preventing ovarian hormone deficiency-inducednhyperlipidaemia.