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Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer

机译：循环microRNA-92a和microRNA-21作为原发性乳腺癌的新型微创生物标志物

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摘要

PurposeMicroRNAs (miRNAs) play an essential role in breast malignant tumor development and progression. The development of clinically validated biomarkers for primary breast cancer (BC) has remained an insurmountable task despite other advances in the field of cancer molecular biology. The objective of this study is to investigate the differential expression of miRNAs and the potential of circulating microRNAs as novel primary breast cancer biomarkers.

机译：目的MicroRNA（miRNA）在乳腺恶性肿瘤的发生和发展中起着至关重要的作用。尽管在癌症分子生物学领域取得了其他进展，但临床验证的原发性乳腺癌（BC）生物标志物的开发仍然是一项不可克服的任务。这项研究的目的是研究miRNA的差异表达和循环microRNA作为新型原发性乳腺癌生物标志物的潜力。

著录项

期刊名称 Springer Open Choice
作者
Haiyan Si; Xiaoming Sun; Yingjian Chen; Yuan Cao; Shimin Chen; Huanchun Wang; Chengjin Hu;
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作者单位

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年(卷),期 -1(139),2
年度 -1
页码 223–229
总页数 7
原文格式 PDF
正文语种
中图分类外科学;
关键词
Breast cancer microRNA miR-92a miR-21 KLK5 qRT-PCR;

机译：乳腺癌;microRNA;miR-92a;miR-21;KLK5;qRT-PCR;

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专利

1. Circulating microRNAs as novel minimally invasive biomarkers for breast cancer. [J] . Heneghan HM, Miller N, Lowery A Annals of Surgery . 2010,第3期

机译：循环microRNAs作为乳腺癌的新型微创生物标志物。
2. Investigation of Plasma cell‐free cancer genome chromosomal instability as a tool for targeted minimally invasive biomarkers for primary liver cancer diagnoses [J] . Shuang Feng, Zhiwen Ding, Jin Wang, Cancer Medicine . 2020,第14期

机译：对血浆细胞无细胞癌基因组染色体稳定性的研究作为针对原发性肝癌诊断的靶向微创生物标志物的工具
3. Discovery of potential serum and urine-based microRNA as minimally-invasive biomarkers for breast and gynecological cancer [J] . Ritter Andrea, Hirschfeld Marc, Berner Kai, Mathematical research letters: MRL . 2020,第2期

机译：发现潜在的血清和基于尿的微小RNA，作为乳腺癌和妇科癌症的微创生物标志物
4. Dual-function biomarkers for detection of breast cancer and its cancer type: Invasive versus non-invasive [C] . Zhang Fan, Liu Tao, Wang Mu, IEEE International Conference on Bioinformatics and Biomedicine . 2013

机译：用于检测乳腺癌及其癌症类型的双功能生物标志物：有创与无创
5. Development of a minimally invasive molecular biomarker for early detection of lung cancer. [D] . Perez-Rogers, Joseph F. 2017

机译：开发用于早期检测肺癌的微创分子生物标志物。
6. Plasma exosome-encapsulated microRNA-21 and microRNA-92a are promising biomarkers for the prediction of peritoneal recurrence in patients with gastric cancer [O] . Naruyoshi Soeda, Hisae Iinuma, Yusuke Suzuki, -1

机译：血浆囊泡包裹的microRNA-21和microRNA-92a是有前景的预测胃癌患者腹膜复发的生物标志物
7. Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer [O] . Haiyan Si, Xiaoming Sun, Yingjian Chen, 2012

机译：循环microRNA-92a和microRNA-21作为原发性乳腺癌的新型微创生物标志物
8. Non-Invasive Screening for Breast Cancer Biomarkers in Nipple Aspirates by Mass Spectrometry [R] . Chang, H. R. 2002

机译：通过质谱法对乳头吸出物中的乳腺癌生物标志物进行非侵入性筛选

Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer

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