Effective Dose of Alaska Pollack Protein for Increase of Muscle

摘要

We have confirmed that the administration of Alaska pollack protein (APP) diet, which was totally substituted APP for casein (Cas) in the AIN-93 diet significantly increased rat skeletal muscle in 3 days after administration, compared to Cas-based control diet. But the administration of amino acid mixture, which of the equivalent amino acid composition to APP, was not effective in increasing skeletal muscle. It suggested that a protein or a degraded peptide of APP might be involved in the efficacy by administration of APP, but not the amino acids. In further study, we plan to investigate the effect of the administration of APP in the clinical trial. For estimation of the dosage for humans, we investigated the effective dose of APP for the skeletal muscle increasing effect of rat.