Anti-programmed cell death protein 1-induced lichenoid changes of the nail unit: Histopathologic description

摘要

Clinical pictures of nail changes in 2 men with lung cancer treated with nivolumab. A, Patient 1, after 20 cycles of nivolumab. The fourth and fifth fingers presented a red lunula, and the first and third fingers presented onycholysis, thinning, and destruction of the nail plate. B, Patient 2, after 39 cycles of nivolumab. Diffuse distal onycholysis on all fingernails.