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Intratumoral Gene Electrotransfer of Plasmid DNA Encoding shRNA against Melanoma Cell Adhesion Molecule Radiosensitizes Tumors by Antivascular Effects and Activation of an Immune Response

机译：黑色素瘤细胞粘附分子的shRNA质粒DNA的瘤内基因电转移通过抗血管作用和免疫应答的激活使肿瘤放射增敏。

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期刊名称 Vaccines
作者
Simona Kranjc Brezar; Valter Mrak; Masa Bosnjak; Monika Savarin; Gregor Sersa; Maja Cemazar;
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作者单位

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年(卷),期 2020(8),1
年度 2020
页码 -1
总页数 19
原文格式 PDF
正文语种
中图分类分子生物学;
关键词
melanoma cell adhesion molecule; siRNA; gene electrotransfer; irradiation; vascular targeted effect; immune response; mouse melanoma model; mouse carcinoma model;

机译：黑色素瘤细胞粘附分子siRNA基因电转移辐射血管靶向作用免疫应答小鼠黑素瘤模型小鼠癌模型;

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专利

1. Electrotransfer of Plasmid DNA Encoding an Anti-Mouse Endoglin (CD105) shRNA to B16 Melanoma Tumors with Low and High Metastatic Potential Results in Pronounced Anti-Tumor Effects [J] . Tanja Dolinsek, Gregor Sersa, Lara Prosen, Cancers . 2016,第1期

机译：编码抗小鼠内皮糖蛋白（CD105）shRNA的质粒DNA电转移至B16黑色素瘤肿瘤，具有低和高转移潜力，可产生明显的抗肿瘤作用
2. Electrotransfer of Plasmid DNA Encoding an Anti-Mouse Endoglin (CD105) shRNA to B16 Melanoma Tumors with Low and High Metastatic Potential Results in Pronounced Anti-Tumor Effects [J] . Gabi Dachs, Gregor Sersa, Lara Prosen, Cancers . 2015,第1期

机译：编码抗小鼠内皮糖蛋白（CD105）shRNA的质粒DNA电转移至B16黑色素瘤肿瘤，具有低和高转移潜力，可产生明显的抗肿瘤作用
3. Electrotransfer of plasmid DNA radiosensitizes B16F10 tumors through activation of immune response [J] . Monika Savarin, Urska Kamensek, Maja Cemazar, Radiology and Oncology . 2017,第1期

机译：质粒DNA的电转移通过激活免疫应答来放射增敏B16F10肿瘤
4. Generation of protective immune response against the P815 tumor by DNA electrotransfer [C] . G. Vandermeulen, C. Uyttenhove, E. De Plaen, Annual meeting exposition of the Controlled Release Society . 2010

机译：通过DNA电转移产生针对P815肿瘤的保护性免疫应答
5. Adenovirus- and cationic-lipid-mediated intratumoral gene transfer and natural killer cell activity in a SCID mouse melanoma tumor model. [D] . Clark, Paul Robert. 1999

机译：在SCID小鼠黑素瘤肿瘤模型中，腺病毒和阳离子脂质介导的肿瘤内基因转移和自然杀伤细胞活性。
6. Electrotransfer of Plasmid DNA Encoding an Anti-Mouse Endoglin (CD105) shRNA to B16 Melanoma Tumors with Low and High Metastatic Potential Results in Pronounced Anti-Tumor Effects [O] . Tanja Dolinsek, Gregor Sersa, Lara Prosen, 2016

机译：编码抗小鼠内皮糖蛋白（CD105）shRNA的质粒DNA电转移至B16黑色素瘤肿瘤具有低和高转移潜力可产生明显的抗肿瘤作用
7. Electrotransfer of Plasmid DNA Encoding an Anti-Mouse Endoglin (CD105) shRNA to B16 Melanoma Tumors with Low and High Metastatic Potential Results in Pronounced Anti-Tumor Effects [O] . Tanja Dolinsek, Gregor Sersa, Lara Prosen, 2015

机译：将编码抗小鼠内皮糖蛋白（CD105）shRNa的质粒DNa电转移至具有低和高转移潜能的B16黑素瘤肿瘤导致显着的抗肿瘤效应

Intratumoral Gene Electrotransfer of Plasmid DNA Encoding shRNA against Melanoma Cell Adhesion Molecule Radiosensitizes Tumors by Antivascular Effects and Activation of an Immune Response

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