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Non-Carcinogenic Health Risk Assessment due to Fluoride Exposure from Tea Consumption in Iran Using Monte Carlo Simulation

机译:使用蒙特卡洛模拟评估伊朗茶叶中的氟化物暴露引起的非致癌健康风险评估

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摘要

Excessive intake of fluoride can cause adverse health effects. Consumption of tea as a popular drink could be a potential source of fluoride exposure to humans. This research aimed to evaluate the fluoride concentration in tea among the Iranian people using the available data in the literature and to assess the health risk related to the consumption of tea in men, women, and children. The health risk assessment was conducted using the chronic daily intake and hazard quotient according to the approach suggested by the Environmental Protection Agency. The fluoride content in published studies varied noticeably, ranging from 0.13 to 3.27 mg/L. The results revealed that the hazard quotient (HQ) in age groups of women (21–72 years) and children (0–11 years) was within the safe zone (HQ < 1) which showed that there was no potential of non-carcinogenic risk associated with drinking tea in these groups. However, in one case of the men (21–72 years), the HQ > 1 which shows a probable risk of fluorosis. The order of non-carcinogenic health risks in the studied groups was in the order of men > women > children. The results of this can be useful for organizations with the responsibility of human health promotion.
机译:摄入过量的氟化物会对健康造成不利影响。喝茶作为一种流行的饮料,可能是氟化物暴露于人类的潜在来源。这项研究旨在利用文献中的可用数据评估伊朗人茶中的氟化物浓度,并评估与男性,女性和儿童饮茶有关的健康风险。根据环境保护署建议的方法,使用慢性每日摄入量和危害商数进行健康风险评估。已发表的研究中的氟化物含量显着变化,范围为0.13至3.27 mg / L。结果表明,妇女(21-72岁)和儿童(0-11岁)年龄组的危险系数(HQ)在安全区域(HQ <1)之内,这表明没有潜在的非致癌性这些人群中与喝茶有关的风险。但是,在一例男性(21-72岁)中,HQ> 1,表明可能患有氟中毒。在研究组中,非致癌健康风险的顺序为男性>女性>儿童。其结果对于负责促进人类健康的组织可能是有用的。

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