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Non-carcinogenic risk assessment to human health due to intake of fluoride in the groundwater in rural areas of Gonabad and Bajestan, Iran: A case study

机译:伊朗Gonabad和Bajestan农村地区地下水中氟化物的摄入对人类健康的非致癌风险评估:一个案例研究

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摘要

In this study, a field research regarding groundwater contamination with fluoride and its related health risks to human health was carried out in 39 rural areas of Gonabad and Bajestan, Iran, in 2017. The results indicated that fluoride levels in two rural areas exceeded the WHO guideline. A total of 55% and 4.7% of the studied rural areas in Gonabad and Bajestan, respectively, had fluoride levels below the minimum recommended value of WHO for fluoride (0.5 mg/L). In this article, chronic non-cancer risks to three different groups of people, adults, children, and infants, for exposure to the fluoride were assessed. Health risk index values for fluoride contamination for 44% and 90% of children and infants in rural areas of Gonabad and Bajestan, respectively, were more than unity (1), which clearly reveals that these age groups at the studied areas are at the chronic health risk due to the intake of fluoride-containing water. The order of fluoride contribution to non-carcinogenic health risk among the studied age groups was infants children adults. Therefore, from a public health viewpoint, it would be prudent and important that risk reduction measures be implemented to diminish the total body burden of fluoride in residents.
机译:在这项研究中,2017年在伊朗的Gonabad和Bajestan的39个农村地区进行了地下水中氟化物污染及其对人类健康的相关健康风险的实地研究。结果表明,两个农村地区的氟化物含量超过了WHO准则。在戈纳巴德和巴杰斯坦的研究农村地区,分别有55%和4.7%的氟化物含量低于WHO对氟化物的最低推荐值(0.5 mg / L)。在本文中,评估了三类不同人群(成年人,儿童和婴儿)因暴露于氟化物而造成的慢性非癌风险。戈纳巴德和巴赫斯坦农村地区分别有44%和90%的儿童和婴儿的氟化物污染健康风险指数值均大于1(> 1),这清楚地表明,所研究地区的这些年龄组处于摄入含氟水对慢性健康有危害。在研究的年龄组中,氟化物对非致癌健康风险的贡献顺序为婴儿>儿童>成人。因此,从公共卫生的角度来看,采取降低风险的措施以减轻居民体内氟化物的总体负担将是审慎和重要的。

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