Monte Carlo k-wave PHOTOACOUSTIC SIGNAL MAGNITUDE ESTIMATION METHOD USING MONTE CARLO AND K-WAVE SIMULATIONS OPTICAL ABSORPTION AND OPTICAL SCATTERING DEGREE CALCULATION METHOD AND PHOTOACOUSTIC CONTRAST WITH THE CORRESPONDING VALUES

摘要

The present invention relates to a method for predicting the magnitude of a photoacoustic signal using Monte Carlo and k-wave simulations, a method for calculating a light absorption degree and a light scattering degree, and a photoacoustic contrast agent with corresponding values. The method for predicting the magnitude of a photoacoustic signal using Monte Carlo and k-wave simulations according to an embodiment of the present invention includes the steps of: calculating an optical fluence; calculating a light absorption coefficient; generating a virtual photoacoustic signal; calculating the transfer of the virtual photoacoustic signal using the simulation; and predicting the magnitude of the photoacoustic signal in an ultrasonic transducer. The method for calculating a light absorption degree and a light scattering degree according to an embodiment of the present invention includes the steps of: calculating the light absorption coefficient; calculating a light extinction degree; calculating the light absorption degree; and calculating the light scattering degree. The present invention can develop the photoacoustic contrast agent with the light absorption coefficient capable of maximizing the photoacoustic signal.