The Active Components in Whole Grain Wheat for Colon Cancer Prevention: Synergistic Effects Between Phytochemical Alkylresorcinols and Fiber Microbial Metabolite Butyrate

摘要

Wheat bran (WB) is a rich source of dietary fiber and phytochemicals with health-promoting properties. However, the active components especially the interaction between different components in whole grain (WG) wheat have not been fully explored. This study aimed to investigate whether WB phytochemicals, alkylresorcinols (ARs), and the active intestinal microbial metabolite of fiber, butyrate, could synergistically suppress human colon cancer cells.