首页> 外国专利> Pharmaceutical active substance, for the treatment of cancers of liver, colon and kidney, comprises a peptide toxin, enzymes and alternatively antagonistically and/or synergistically active substance

Pharmaceutical active substance, for the treatment of cancers of liver, colon and kidney, comprises a peptide toxin, enzymes and alternatively antagonistically and/or synergistically active substance

机译:用于治疗肝癌,结肠癌和肾癌的药物活性物质包括肽毒素,酶以及拮抗和/或协同活性物质

摘要

A pharmaceutical active substance (I), for the treatment of cancers of liver, colon and kidney, comprises a peptide toxin (A), 5 enzymes (B), alternatively at least one antagonistically and/or synergistically active substance, where two enzymes are obtained from Crotalus durissus durissus. A pharmaceutical active substance (I), for the treatment of cancers of liver, colon and kidney, comprises at least a peptide toxin (A), 5 enzymes (B), alternatively at least one antagonistically and/or synergistically active substance, where two enzymes are obtained from Crotalus durissus durissus and at least (A), (B), antagonistically and/or synergistically active substance derived from the toxin of spiders (Sicarius albospinosus or Loxosceles berger), animals (Scolopendra subspinipes), snakes (Crotalus durissus durissus) and reptiles (Heloderma) or ant (bull ant type), and the specified substances have a molecular weight of 3-60 kDa. Independent claims are also included for (1) a pharmaceutical active substance for the treatment of cancers of liver, colon and kidney, comprises either at least (A) or (B), at least one antagonistically and/or synergistically active substance, where two enzymes are obtained by Crotalus durissus durissus; or at least (A) or (B) and antagonistically/synergistically active substance derived from the toxin of spiders (Sicarius albospinosus or Loxosceles berger), animals (Scolopendra subspinipes), snakes (Crotalus durissus durissus), reptiles (Heloderma) or ant (bull ant) and the specified substances have a molecular weight of 3-60 kDa; and (2) the preparation of (I). ACTIVITY : Cytostatic; Antibacterial; Fungicide; Antitubercular; Tuberculostatic; Antiparasitic. MECHANISM OF ACTION : Peptide therapy; Antagonist; Synergist.
机译:用于治疗肝癌,结肠癌和肾癌的药物活性物质(I)包含肽毒素(A),5种酶(B),或者至少一种拮抗和/或协同活性物质,其中两种酶是从猪屎豆属获得。用于治疗肝癌,结肠癌和肾癌的药物活性物质(I)包含至少一种肽毒素(A),5种酶(B),或者至少一种拮抗和/或协同活性物质,其中两种酶得自猪屎豆和至少(A),(B)来源于蜘蛛(Sicarius albospinosus或Loxosceles berger)毒素,动物(Scolopendra subspinipes),蛇(Crotalus durissus durissus)毒素的拮抗和/或协同活性物质)和爬行动物(Heloderma)或蚂蚁(牛蚁型),指定的物质的分子量为3-60 kDa。还包括针对以下方面的独立权利要求:(1)用于治疗肝癌,结肠癌和肾癌的药物活性物质,其包含至少(A)或(B),至少一种拮抗和/或协同活性物质,其中两种酶是由猪屎豆制成的;或至少(A)或(B)以及源自蜘蛛(Sicarius albospinosus或Loxosceles berger),动物(Scolopendra subspinipes),蛇(Crotalus durissus durissus),爬行动物(Heloderma)或蚂蚁(毒素)的毒素的拮抗/协同活性物质Bullant)和指定物质的分子量为3-60 kDa; (2)制备(I)。活动:细胞抑制;抗菌;杀菌剂抗结核结核病;抗寄生虫。作用机理:肽疗法;拮抗剂增效剂。

著录项

  • 公开/公告号DE102004008417A1

    专利类型

  • 公开/公告日2005-09-08

    原文格式PDF

  • 申请/专利权人 TOXIMED GMBH;

    申请/专利号DE20041008417

  • 发明设计人 WEICKMANN DIRK;

    申请日2004-02-20

  • 分类号A61K38/43;A61P35/00;

  • 国家 DE

  • 入库时间 2022-08-21 22:00:53

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