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VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML

机译：VISTA在MDSCs上高表达并介导AML患者T细胞反应的抑制

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期刊名称 Oncoimmunology
作者
Liru Wang; Bei Jia; David F. Claxton; W Christopher Ehmann; Witold B. Rybka; Shin Mineishi; Seema Naik; Muhammad R. Khawaja; Jeff Sivik; Junyan Han; Raymond J. Hohl; Hong Zheng;
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年(卷),期 2018(7),9
年度 2018
页码 e1469594
总页数 10
原文格式 PDF
正文语种
中图分类
关键词
Acute myeloid leukemia (AML) VISTA programmed cell death protein 1 (PD-1) immunotherapy;

机译：急性粒细胞白血病（AML）;VISTA;程序性细胞死亡蛋白1（PD-1）;免疫疗法;

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专利

1. VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML [J] . Liru Wang, Bei Jia, David F. Claxton, Oncoimmunology. . 2018,第9期

机译：Vista在MDSCS上高度表达，并介导AML患者的T细胞应答抑制
2. Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells [J] . Juan Bautista Menendez-Gonzalez, Samantha Sinnadurai, Alex Gibbs, Scientific reports. . 2019,第1期

机译：抑制GATA2抑制细胞增殖，并增强人类GATA2过表达AML细胞的凋亡和化疗介导的凋亡
3. Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition [J] . Greiner Jochen, Goetz Marlies, Hofmann Susanne, Cancer immunology, immunotherapy : . 2020,第4期

机译：通过免疫检查点抑制增加了针对包括白血病患者白血病祖细胞的菌落形成细胞的特异性T细胞免疫应答
4. Modulation of Cellular Behavior by Inhibition of Intracellular Enzymes to Enhance in vitro Transient Non‐Viral Polymer‐Mediated Transgene Expression [C] . Matthew Christensen, Jacob Elmer, Sutapa Barua AIChE Annual Meeting . 2014

机译：通过抑制细胞内酶来增强体外瞬时非病毒聚合物介导的转基因表达的调节
5. Mechanisms mediating tocotrienol derivative in vitro and in vivo anticancer effects and inhibition of compensatory responses to hypoxia in the highly malignant mouse +SA mammary cancer cells. [D] . Ananthula, Suryatheja. 2014

机译：在高度恶性的小鼠+ SA乳腺癌细胞中介导生育三烯酚衍生物的体内外抗癌作用和对缺氧的代偿反应的抑制机制。
6. Arginase-1 is neither constitutively expressed in nor required for myeloid-derived suppressor cell (MDSC)-mediated inhibition of T cell proliferation [O] . Zhen Bian, Ahmed Mansour Abdelaal, Lei Shi, -1

机译：Arginase-1既不组成性表达也不是髓样抑制细胞（MDSC）介导的T细胞增殖抑制所必需的
7. VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML [O] . Liru Wang, Bei Jia, David F. Claxton, 2018

机译：Vista在MDSCS上表达高度表达，并介导AML患者的T细胞反应抑制

VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML

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