Identification of rare copy number variations reveals PJA2 APCS SYNPO and TAC1 as novel candidate genes in Autism Spectrum Disorders

摘要

BackgroundThere is a strong evidence for genetic factors as the main causes of Autism Spectrum Disorders (ASD). To date, hundreds of genes have been identified either by copy number variations (CNVs) and/or single nucleotide variations. However, despite all the findings, the genetics of these disorders have not been totally explored.