METHOD FOR TREATING AUTISM SPECTRUM DISORDER, MOUSE FOR MONITORING AUTISM SPECTRUM DISORDER, AND METHOD FOR SCREENING CANDIDATE MATERIAL FOR PREVENTING OR TREATING AUTISM SPECTRUM DISORDER

摘要

The present invention relates to a method for treating autism spectrum disorder, a mouse for monitoring autism spectrum disorder, and a method for screening a candidate material for preventing or treating autism spectrum disorder. Specifically, after introducing halorhodopsin protein into neurons of the ventrolateral thalamus (VL), the laterodorsal thalamus (LD), or the striatum, halorhodopsin protein is induced to undergo hyperpolarization by exposure to light, thereby suppressing output signals (or collective excitement) of the ventrolateral thalamus (VL), the laterodorsal thalamus (LD), or the striatum neurons, thereby having an effect of preventing or treating autism.;COPYRIGHT KIPO 2020