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Partial duplication of the PRLR and SPEF2 genes at the late feathering locus in chicken

机译:PRLR和SPEF2基因在鸡的晚期羽化基因座上的部分复制

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摘要

BackgroundOne of the loci responsible for feather development in chickens is K. The K allele is partially dominant to the k+ allele and causes a retard in the emergence of flight feathers at hatch. The K locus is sex linked and located on the Z chromosome. Therefore, the locus can be utilized to produce phenotypes that identify the sexes of chicks at hatch. Previous studies on the organization of the K allele concluded the integration of endogenous retrovirus 21 (ev21) into one of two large homologous segments located on the Z chromosome of late feathering chickens. In this study, a detailed molecular analysis of the K locus and a DNA test to distinguish between homozygous and heterozygous late feathering males are presented.
机译:背景技术鸡中羽毛发育的一个基因座是K。K等位基因在k +等位基因中部分占优势,并会导致孵化中飞羽的出现受到阻碍。 K基因座是性别相关的,位于Z染色体上。因此,该基因座可用于产生识别出孵化雏鸡性别的表型。先前有关K等位基因组织的研究得出结论,将内源性逆转录病毒21(ev21)整合到位于晚羽鸡Z染色体上的两个大同源区段之一中。在这项研究中,提出了详细的K位点分子分析和DNA测试,以区分纯合和杂合晚羽雄性。

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