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Exploring the gene–environment nexus in eating disorders

机译:探索饮食失调的基因与环境的联系

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摘要

Early theories of eating disorders focused on aversive family and sociocultural factors as fundamental to the development of these problems. A progression of family, twin and molecular genetic studies has demonstrated a substantial role for genetic factors in the development of anorexia nervosa, bulimia nervosa and related traits. Paradoxically, genetic studies hold promise for refining and enriching our approach to understanding the impact of adverse environmental forces. The development of new and more sophisticated approaches for understanding the complex interplay of genetic and environmental effects will allow enhanced understanding of both risk and protective environmental factors and how they may influence expressions of underlying genetic vulnerabilities to eating disorders.
机译:饮食失调的早期理论集中在厌恶家庭和社会文化因素上,这些因素是导致这些问题发展的基础。家庭,双胞胎和分子遗传学研究的进展表明遗传因素在神经性厌食症,神经性贪食症和相关性状的发展中起着重要作用。矛盾的是,遗传学研究有望完善和丰富我们了解不利环境力量影响的方法。通过开发新的,更先进的方法来理解遗传和环境影响之间复杂的相互作用,将使人们更加了解风险和保护性环境因素,以及它们如何影响进食障碍的潜在遗传脆弱性表达。

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