BAL fluid cells in newly diagnosed pulmonary sarcoidosis with different clinical activity

摘要

BackgroundSarcoidosis is associated with an increase in the number of alveolar T cells (CD3⁺ cells) and an increase of the CD3⁺CD4⁺ lymphocyte subset. However, the number of lymphocytes and the CD4/CD8 ratio in bronchoalveolar lavage (BAL) fluid are highly variable in sarcoidosis. Comparative studies have demonstrated that geographic and ethnic factors are linked to the specific characteristics of patients with sarcoidosis.