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Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report

机译:单纯刮除不加植骨治疗胫骨动脉瘤性骨囊肿实变体:一例

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摘要

The solid variant of aneurysmal bone cyst (solid ABC) is rarely encountered in long bones and appropriate treatment for this disease remains unclear. We experienced a 13-year-old boy suffering from pain in his left knee caused by solid ABC. Simple curettage of the bone lesion without any adjuvant therapy and a bone graft gave immediate pain relief. Histological examination of the surgical specimen showed typical features of solid ABC, and cycloxygenase-2 (COX-2) expression was confirmed in giant cells with a background of spindle cells by immunohistochemistry. Magnetic resonance imaging showed that soft tissue edema surrounding the lesion was improved two months after surgery and there was no indication of recurrence two years after surgery.If COX-2 secreted from the tumor induces soft tissue edema, simple curettage of the bone lesion seems to be a reasonable treatment for solid ABC and is able to minimize invasive treatment of the patients.
机译:在长骨中很少见到动脉瘤性骨囊肿的实心变体(实心ABC),尚不清楚对该疾病的适当治疗方法。我们经历了一个13岁的男孩,他的左膝疼痛是由坚实的ABC引起的。简单刮除骨病变无需任何辅助治疗和植骨即可立即缓解疼痛。手术标本的组织学检查显示了固体ABC的典型特征,并通过免疫组织化学证实了以梭形细胞为背景的巨细胞中环氧合酶2(COX-2)的表达。磁共振成像显示,手术后两个月病变周围的软组织水肿得到改善,手术后两年未见复发迹象。如果肿瘤分泌的COX-2引起软组织水肿,则单纯刮除骨病变似乎是是固体ABC的合理治疗方法,能够最大程度地减少对患者的侵入性治疗。

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