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Osteoblastoma of the Lateral Skull Base: Work-Up Surgical Management and a Review of the Literature

机译:颅骨外侧成骨细胞瘤:检查手术处理和文献复习

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摘要

>Objectives To describe the work-up and surgical management of an osteoblastoma involving the lateral skull base. Typically occurring in the spine or long bones, osteoblastomas of the craniofacial skeleton are exceedingly rare and infrequently reported. A review of the current literature regarding temporal bone osteoblastoma, diagnosis, and treatment is described.>Methods This case report describes the clinical presentation, radiographic studies, surgical management, histology, and postoperative follow-up of a young man presenting to a tertiary care neurotology practice with osteoblastoma involving the lateral skull base. A review of the current literature regarding osteoblastoma of the skull base, work-up, and treatment is described.>Results A 15-year-old adolescent boy with a greater than 1-year history of right-sided retroauricular pain, a palpable postauricular mass, and chronic headaches presented for evaluation/management. Microscope examination of the ears, hearing, and cranial nerve function were normal. High-resolution temporal bone computed tomography and magnetic resonance imaging scans were obtained, which revealed an expansile mass involving the junction of the temporal and occipital bones. The patient underwent a combined retrosigmoid/retrolabyrinthine resection of this extradural tumor. Histology revealed a benign bone neoplasm consistent with osteoblastoma. Complete surgical resection was achieved, and the patient's symptoms fully resolved. Follow-up imaging studies found no evidence of recurrence. The scientific literature relevant to work-up and management of osteoblastoma is reviewed.>Discussion Osteoblastomas of the lateral skull base are rare, histologically benign tumors that can present with radiographic features suggestive of malignancy. An en bloc resection is important for both diagnosis and definitive treatment of these neoplasms. The differential diagnosis on imaging and histology is discussed.
机译:>目的描述涉及颅骨外侧基底的成骨细胞瘤的检查和外科治疗。颅面骨骼的成骨细胞瘤通常发生在脊柱或长骨中,极为罕见,很少报道。描述了有关颞骨成骨细胞瘤,诊断和治疗的最新文献。>方法该病例报告描述了一名年轻患者的临床表现,影像学检查,外科治疗,组织学和术后随访人正在向涉及颅骨外侧基底的成骨细胞瘤的三级护理神经病学实践。描述了有关颅底成骨细胞瘤,检查和治疗的最新文献。>结果一名15岁的青春期男孩,其右侧病史超过1年出现耳后疼痛,明显的耳后肿块和慢性头痛,以进行评估/治疗。耳朵,听力和颅神经功能的显微镜检查均正常。获得了高分辨率颞骨计算机体层摄影术和磁共振成像扫描,结果显示涉及颞骨和枕骨交界处的可膨胀肿块。患者对该硬膜外肿瘤进行了乙状结肠/后迷路联合联合切除。组织学显示与成骨细胞瘤一致的良性骨肿瘤。手术完全切除,患者的症状得到完全缓解。后续影像学检查未发现复发迹象。综述与成骨细胞瘤的处理和管理有关的科学文献。>讨论颅骨外侧基底的成骨细胞瘤是罕见的,在组织学上良性的肿瘤,可表现出提示恶性的影像学特征。整体切除对于这些肿瘤的诊断和确定性治疗都很重要。讨论了影像学和组织学的鉴别诊断。

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