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Serum levels of β-hydroxybutyrate and pyruvate metabolic changes and cognitive function in patients with schizophrenia during antipsychotic treatment: a preliminary study

机译：抗精神病药物治疗期间精神分裂症患者的血清β-羟基丁酸和丙酮酸水平代谢变化和认知功能的初步研究

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摘要

Backgroundβ-hydroxybutyrate (β-HB) and pyruvate have been associated with the brain energy utilization, which may play a role in the pathophysiology of schizophrenia. In this prospective study, we aim to investigate the trends of β-HB and pyruvate levels, metabolic changes, and cognitive function in schizophrenia patients receiving antipsychotic treatment.

机译：背景β-羟基丁酸酯（β-HB）和丙酮酸与脑能量利用有关，可能在精神分裂症的病理生理中起作用。在这项前瞻性研究中，我们旨在研究接受抗精神病药物治疗的精神分裂症患者的β-HB和丙酮酸水平，代谢变化和认知功能的趋势。

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期刊名称 Neuropsychiatric Disease and Treatment
作者
Yu-Chi Huang; Pao-Yen Lin; Yu Lee; Chi-Fa Hung; Su-Ting Hsu; Chih-Ching Wu; Liang-Jen Wang;
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作者单位

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年(卷),期 2018(14),-1
年度 2018
页码 799–808
总页数 10
原文格式 PDF
正文语种
中图分类神经病学;精神病学;
关键词
ketone body energy metabolism executive function cognition antipsychotic schizophrenia;

机译：酮体;能量;新陈代谢;执行功能;认知;抗精神病药;精神分裂症;

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专利

1. Serum levels of β-hydroxybutyrate and pyruvate, metabolic changes and cognitive function in patients with schizophrenia during antipsychotic treatment: a preliminary study [J] . Yu-Chi Huang, Pao-Yen Lin, Yu Lee, Neuropsychiatric Disease and Treatment . 2018,第1期

机译：抗精神病药物治疗期间精神分裂症患者的血清β-羟基丁酸和丙酮酸水平，代谢变化和认知功能的初步研究
2. Relationship of serum testosterone levels with cognitive function in chronic antipsychotic-treated male patients with schizophrenia [J] . Li Jin, Xiao Wenhuan, Sha Weiwei, Asia-Pacific psychiatry: official journal of the Pacific Rim College of Psychiatrists . 2015,第3期

机译：慢性抗精神病药物治疗的男性精神分裂症患者血清睾丸激素水平与认知功能的关系
3. Plasma levels of 3-methoxy-4-hydroxyphenylglycol levels, number of hospitalization and cognitive function predicts the cognitive effect of atypical antipsychotic monotherapy in patients with acute schizophrenia [J] . Trends in Ecology & Evolution . 2020,第2期

机译：3-甲氧基-4-羟基苯乙二醇水平，住院和认知函数的血浆水平预测急性精神分裂症患者的非典型抗精神单药治疗的认知效果
4. COMT gene polymorphism and antipsychotic- induced hyperprolactinemia in schizophrenia patients [C] . Svetlana Ivanova, Diana Paderina, Anastasiia Boiko, Conference on Cognitive Sciences, Genomics and Bioinformatics . 2020

机译：精神分裂症患者COMT基因多态性与抗精神病药诱发的高泌乳素血症
5. Effectiveness and Tolerability (with focus on metabolic effects) of Atypical Antipsychotics in the Treatment of Schizophrenia: A 48-weeks Noninterventional Naturalistic Comparative Study. [D] . Surti, Bakulesh B. 2013

机译：非典型抗精神病药治疗精神分裂症的有效性和耐受性（重点在于代谢作用）：一项48周的非干预性自然主义比较研究。
6. The effect of atypical antipsychotics on brain N-acetylaspartate levels in antipsychotic-naïve first-episode patients with schizophrenia: a preliminary study [O] . Vladimir Grošić, Petra Folnegović Grošić, Petra Kalember, 2014

机译：非典型抗精神病药对首次服用抗精神病药的精神分裂症患者脑中N-乙酰天冬氨酸水平的影响：初步研究
7. Serum levels of beta;-hydroxybutyrate and pyruvate, metabolic changes and cognitive function in patients with schizophrenia during antipsychotic treatment: a preliminary study [O] . Yu-Chi Huang, Pao-Yen Lin, Yu Lee, 2018

机译：抗精神病药治疗期间精神分裂症患者的β-羟基丁酸酯和丙酮酸血清水平，代谢变化和认知功能：初步研究

Serum levels of β-hydroxybutyrate and pyruvate metabolic changes and cognitive function in patients with schizophrenia during antipsychotic treatment: a preliminary study

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