Clinicopathologic features of plasmablastic lymphoma: Single-center series of 8 cases from Saudi Arabia

摘要

BackgroundPlasmablastic lymphoma (PBL) is a rare subtype of non-Hodgkin’s lymphoma. Characterized by its aggressive nature and plasmacytic differentiation, PBL remains a therapeutic and diagnostic challenge; it generally has a poor prognosis with very few long-term survivors and most patients dying within 2 years from initial presentation.PBL has been reported in several other countries; however, there have been no reported cases from Saudi Arabia. Here, we report 8 cases of PBL depicting the clinical presentation, immunocompetency, immunphenotypic characterization, diagnostic challenges and treatment outcome.