动态浊度法定量检测葡萄糖甘露醇注射液中细菌内毒素

摘要

OBJECTIVE To detect the quantity of bacterial endotoxin in glucose mannitol injection by kinetic turbidimetric assay.METHODS Kinetic turbidimetric assay for bacterial endotoxin test was used according to Chp2010.RESULTS 1∶4solutionofglucosemannitolinjectionshowednointerferenceontestandtherecoverywas 50%~200%.CONCLUSION Turbidimetric assay can be used for bacterial endotoxin test for glucose mannitol injection in daily inspection .%目的：应用动态浊度法定量检测葡萄糖甘露醇注射液中的细菌内毒素。方法采用《中国药典》2010年版附录ⅪE。结果将葡萄糖甘露醇注射液1∶4稀释，回收率在50％～200％，无干扰作用。结论动态浊度法测定葡萄糖甘露醇注射液中的细菌内毒素，结果准确，日常检验是可行的。