碳酸乙烯酯合成3-氨基-2-(噁)唑烷酮的热力学分析

摘要

采用碳酸乙烯酯与水合肼为原料合成了3-氨基-2-(噁)唑烷酮,采用Benson基团贡献法和Joback法对反应的热力学进行分析,计算了反应焓变、吉布斯自由能和反应平衡常数.%3-Amino-2-oxazolidinone is an important raw material for the synthesis of furazolidone.This article put forward a new synthesis process of using ethylene carbonate and hydrazine as raw materials.The reaction thermodynmic was analyzed by Benson Group Contribution method and Joback method.The reaction heat,Gibbs free energy and equilibrium constants of the reaction calculated by the group contribution method and the obtained results can supply guidance for the experimental research and the process scale-up.