Objective To observe the clinical efficacy of acupoint thread embedding in improving aromatase inhibitors (AIs)-induced osteopenia in breast cancer patients. Method Ninety-three patients were randomized into a treatment group and a control group, 47 cases in the treatment group and 46 cases in the control group. The treatment group was intervened by Caltrate and acupoint thread embedding, while the control group was by Caltrate alone. After 6-month treatment, the bone mineral density T scores and estradiol were evaluated. The therapeutic efficacies were also compared between the two groups. Result The T scores increased significantly after the treatment in both groups (P<0.01);the therapeutic efficacy of the treatment group was better than that of the control group (P<0.05). After the intervention, the change of estradiol level in the control group was not discernible. The level of estradiol increased after the treatment in the treatment group, but was insignificantly different from that in the control group (P>0.05). Conclusion Caltrate and acupoint thread embedding can produce a content efficacy in treating AIs-induced osteopenia in breast cancer patients, and can produce certain effects on the estrogens.%目的：观察穴位埋线改善乳腺癌患者芳香化酶抑制剂(aromatase inhibitors,AIs)引起的骨量减少的临床疗效。方法将93例患者随机分为治疗组和对照组,治疗组47例,对照组46例。治疗组予以口服碳酸钙D3加穴位埋线治疗,对照组予以口服碳酸钙D3治疗。治疗6个月后,分别评价两组患者T值及雌二醇水平,并比较两组疗效。结果治疗后治疗组与对照组患者T值均有提高,且均有统计学意义(P＜0.01)；治疗组疗效优于对照组(P＜0.05)。对照组患者雌激素水平波动不明显,治疗组患者雌激素水平增加,但与对照组相比,差异无统计学意义(P＞0.05)。结论碳酸钙D3加穴位埋线对于激素受体阳性乳腺癌患者因AI类药物辅助内分泌治疗引起的骨丢失疗效较好,且对雌激素的代谢水平有一定的影响。
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