目的：探讨青春期多囊暖巢综合征（PCOS）胰岛素抵抗与非胰岛素抵抗患者的生殖内分泌指标的差异。方法：选取2012年6月到2014年6月在我院接受治疗的104例青春期 PCOS患者为研究对象，根据胰岛素抵抗程度分为胰岛素抵抗组（IR 组＝54）与非胰岛素抵抗组（非 IR 组＝50），比较两组的生殖内分泌指数促黄体生成素（LH ）、促卵泡生成素（FSH ）、性激素结合蛋白（SHBG）及睾酮（T ），同时测定体重指数（BMI）、腰臀围比值（WHR）、多毛评分（F‐G 评分）。结果：观察组 LH 、FSH 、SHBG 、均显著低于对照组，组间对比差异显著（ P ＜0．05），观察组的 BMI 、WHRT 指标值及 F‐G 评分显著高于对照组，差异具有统计学意义（P＜0．05）。结论：青春期 PCOS胰岛素抵抗生殖内分泌指标中 LH 、FSH 、SHBG 低于非胰岛素抵抗患者，T 高于非胰岛素抵抗组分泌雄激素能力下降，需注意调节胰岛素的抵抗状态。%Objective :To compare the differences of insulin resistance and insulin resistance in PCOS pa‐tients with reproductive endocrine indexes of adolescence .Methods :Select 104 cases of patients with PCOS from June to 2014 2012 in adolescence February treated in our hospital as the research object ,according to the degree of insulin resistance was divided into insulin resistance group (group IR , = 54) and non insulin resistance group (non IR group , = 50) ,reproductive endocrine indices were compared between the two groups in promoting luteinizing hormone (LH) and promoting follicle stimulating hormone (FSH) ,sex hormone binding globulin (SHBG) and tes‐tosterone (T ) determination of body mass index (BMI) ,waist hip ratio (WHR) ,hirsutism score (F‐G score) .Re‐sults :In the observation group ,LH ,FSH ,SHBG ,T index were significantly lower than those in control group , the difference between the groups was significant (P< 0 .05) ,the observation group of BMI ,WHR and F‐G scores were significantly higher than those in the control group ,with significant difference (P< 0 .05) .Conclusion :Insulin resistance index PCOS of adolescent reproductive endocrine is lower than that in non insulin resistance patients ,an‐drogen secretion capacity decreased ,the need to pay attention to the regulation of insulin resistance state .
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