Methods for determining if a patient resistant to insulin is a responder to a therapeutic treatment for insulin resistance.And to predict if a therapeutic treatment for insulin resistance will be effective in improvement of one or more diseases associated with insulin resistance

摘要

Methods for determining if a patient resistant to insulin is a responder to a therapeutic treatment for insulin resistance.And to predict if a therapeutic treatment for insulin resistance will be effective in improvement of one or more diseases associated with insulin resistance.A patient who is a responder to a therapeutic treatment for insulin resistance or one or more diseases associated with type 2 diabetes can be identified by the method of measuring the quaNtidade of Adiponectin of PMA and the amount of total adiponectin or Adiponectin of PMB in the tissue of the patient (usually the plasma or serum) before the start of the therapeutic treatment; then startTherapeutic treatment; and finally, to measure the amount of Adiponectin of PMA and the amount of total adiponectin and adiponectin or of PMB in plasma or serum of the patient one or more times afterThe beginning of the therapeutic treatment.It is predicted that the patient is the responder to therapeutic treatment is the reason of adiponectin to WFP for the quantity of total adiponectin or Adiponectin of PMB increase after starting treatmentTherapeutic.