首页> 中文期刊> 《陕西医学杂志 》 >新辅助动脉化疗在妇科恶性肿瘤中的临床应用观察

新辅助动脉化疗在妇科恶性肿瘤中的临床应用观察

             

摘要

Objective :To investigate the therapeutic effect of neoadjuvant arterial chemotherapy in gynecolog-ic malignancies .Methods:Sixty-four patients with stage Ib2~ Ⅱb cervical cancer were randomly divided into treat-ment group (34 cases) and control group (30 cases) .Patients in the treatment group received neoadjuvant arterial therapy ;patients in the control group received surgical treatment .Record the intraoperative bleeding in patients ,ob-serve the postoperative pathological conditions ,evaluate the curative effect .Results :The bleeding volume of the treatment group was lower than that of the control group (P<0 .05) .The effective rate of the treatment group was 97 .06% ,significantly higher than that of the control group 80 .00% (P<0 .05) ,1/2(50 .00% ) lymph node metasta-sis (5 .88% ) and vascular tumor thrombus (11 .76% ) were lower than the control group (P<0 .05) .Conclusion :Neoadjuvant arterial chemotherapy can increase the effective treatment rate of cervical cancer patients ,improve the pathological state of cervical cancer patients and reduce the amount of intraoperative blood loss .%目的:探讨新辅助动脉化疗对妇科恶性肿瘤中的治疗效果.方法:选择Ⅰb2~Ⅱb期宫颈癌患者64例,随机分为治疗组(34例)和对照组(30例).治疗组患者接受新辅助动脉疗法;对照组患者进行手术治疗.记录患者术中出血情况,观察术后病理情况,评价疗效.结果:治疗组患者出血量低于对照组(P<0.05);治疗组患者术后有效率为97.06%,明显高于对照组的80.00%(P<0.05),治疗组患者间质浸润≥1/2(50.00%)、淋巴结转移(5.88%)、脉管癌栓(11.76%)比例均小于对照组(P<0.05).结论:新辅助动脉化疗能够增加宫颈癌患者近期治疗有效率,够改善宫颈癌患者术后病理状态,有减少患者术中出血量.

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