Objective To study the risk factors of short-term postoperative recurrence in situ of patients with bone me-tastases treated with operative treatment ,and provide the basis for clinical treatment and prognosis .Methods Whole follow-up data of 96 patients were analyzed retrospectively .The clinical factors,such as gender,age,position,operation method were chosen ,χ2-test were used in single factor analysis and multiple factors logistic regression analysis ,the risk factors of short-term postopera-tive recurrence in situ of patients with bone metastases treated with operative treatment were studied .Results Among 96 cases, recurrence in situ in 6 months was 29 cases,total recurrence rate was 30.2%.Single factor analysis showed that the curative effect of operation for patients was correlated (P<0.05) with operative lesion,operation method,speed of tumor progression,tumor size,ECOG score,preoperative local radiotherapy ,local radiotherapy after operation ,preoperative local radiotherapy from the pri-mary lesion,preoperative sensitive systemic treatment ,postoperative sensitive systemic treatment ,while it had no correlation (P>0.05) with the gender,age,the nature of lesion,orthopedic complications,the outside of bone,internal organs transfer and the number of bone metastases;Multi-factor analysis showed the ECOG score ,speed of tumor progression ,tumor size,operative lesion, former local radiotherapy ,preoperative local radiotherapy from the primary lesion , preoperative sensitive systemic treatment were independent risk factors of short-term postoperative recurrence in situ of patients with bone metastases treated with operative treat -ment.Conclusion The influencing factors of short-term postoperative recurrence in situ of patients with bone metastases treated with operative treatment are ECOG score,speed of tumor progression,tumor size,operative lesion,former local radiotherapy,preop-erative local radiotherapy from the primary lesion ,and preoperative sensitive systemic treatment .In treatment,there should be comprehensive assessment and following the principle of individualization strictly ,there also should be early detection ,early diag-nosis,early treatment,and insist on postoperative follow-up.%目的：探讨影响手术治疗骨转移瘤患者术后短期内原位复发的危险因素，以期为临床治疗及预后判断提供依据。方法回顾性分析96例随访资料完整的病例，选择性别、年龄、部位、手术方式等临床因素，用χ2-test进行单因素分析和Logistic多因素回归分析，分析手术治疗骨转移瘤术后短期内肿瘤原位复发的危险因素。结果96例病例中，6个月内肿瘤原位复发29例，总复发率为30．2％。单因素分析结果显示手术病灶部位、手术方式、肿瘤进展速度、肿瘤大小、ECOG评分、术前局部放疗、术后局部放疗、术前原发病灶局部放疗、术前敏感的全身治疗、术后敏感的全身治疗均与手术治疗骨转移瘤术后短期内肿瘤原位复发具有显著相关性（P＜0．05），而与患者的性别、年龄、病灶性质、骨科并发症、骨外浸润、内脏转移、骨转移灶数目无明显相关性（P＞0．05）；多因素分析结果显示ECOG评分、肿瘤进展速度、肿瘤大小、手术病灶部位、前局部放疗、术前原发病灶局部放疗、术前敏感的全身治疗是影响手术治疗骨转移瘤患者术后短期内原位复发的独立危险因素。结论影响手术治疗骨转移瘤患者术后短期内原位复发的影响因素是ECOG评分、肿瘤进展速度、肿瘤大小、手术病灶部位、前局部放疗、术前原发病灶局部放疗、术前敏感的全身治疗，在治疗上应综合评估及严格遵循个体化原则，早发现、早诊断、早治疗、坚持术后随访。
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